ABSTRACT
Background: Hepatitis C virus (HCV) is a major causative agent of parenterally acquired hepatitis. Vertical transmission of HCV occurs from mother to infant during pregnancy, delivery, or neonatal period. Hepatitis C infection among pregnant females can adversely affect both mother and fetus, leading to chronic infection in infants who later develop liver cirrhosis and hepatocellular carcinoma. Objective of the study was to evaluate the prevalence of hepatitis C among pregnant females attending antenatal clinic.Methods: A hospital based cross-sectional study was done over a period of six months from January to June 2019. A total of 550 pregnant females were included in the study who attended Antenatal Clinic for routine check-up and whose blood samples were sent to Microbiology Laboratory for screening of anti-HCV antibodies by Enzyme linked Immunosorbent Assay (ELISA) method.Results: Out of 550 pregnant females tested, 3 were found to be reactive to anti-HCV antibodies by ELISA; hence the prevalence was found to be 0.5%. All 3 seropositive females belonged to age group 26-35 years, were indoor patients (IPD) and belonged to lower socio-economic class. Majority of seropositive females belonged to urban areas (66.7%, 2/3) as compared to those from rural areas (33.3%, 1/3).Conclusions: Although, prevalence of hepatitis C was found to be less among pregnant females attending ANC of this institute, still routine screening of all pregnant females for anti-HCV antibodies is highly recommended, for timely detection of disease in mothers and prevention of its transmission to infants.
ABSTRACT
Background: Hepatitis B infection is one of the most common public health problems worldwide. Hepatitis B virus Surface Antigen (HBsAg) positive mothers may transmit the virus vertically to neonates transplacentally during pregnancy, perinatally during delivery or postnatally through breast milk. Such neonates being carriers of virus are at a very high risk of developing chronic liver diseases at a younger age and also, they act as reservoirs of infection in the community. Objective of the study is to evaluate the seroprevalence of HBsAg in pregnant females attending Antenatal Clinic.Methods: A hospital based cross-sectional study was done from January to June 2019. A total of 840 pregnant females were included in the study who attended Antenatal Clinic for routine checkup whose blood samples were sent to Microbiology Laboratory for screening of HBsAg by Enzyme Linked Immunosorbent Assay (ELISA).Results: Out of 840 pregnant females included in the study, 8 were reactive to HBsAg, hence, prevalence was found to be 0.95%. The seroprevalence of HBsAg was found to be more (1.40%) in 26-35 year females. Maximum seropositivity was seen in females from urban areas (1.0%), those attending OPD of ANC (1.03%) and those who belonged to lower socio-economic class (1.02%).Conclusions: Routine free screening for HBV infection should be offered to all antenatal females to reduce the risk of vertical transmission to the neonates born to infected mothers, thereby, preventing them from becoming carriers and developing chronic hepatitis and hepatocellular carcinoma later in life.
ABSTRACT
Background: Cesarean section is one of the most commonly performed surgical procedures in obstetrics worldwide. Over the last three decades, a tremendous increase in cesarean section rates has been observed globally, which is a cause for concern as procedure is associated with higher morbidity and mortality compared to vaginal delivery. This study was done to analyze the rate and indications for cesarean section and associated maternal morbidity and mortality.Methods: This retrospective study was conducted over a period of 6 months from 1st October 2017 to 31st March 2018 in the department of Obstetrics and Gynecology, Integral Institute of Medical Sciences and Research, Lucknow, India. Data of patients who were admitted for delivery in department of Obstetrics and Gynecology in OPD or emergency were recorded. Statistical analysis of various parameters namely, the cesarean section rates, its indications, the patient’s morbidity and mortality was done.Results: The total numbers of women delivered over the study period were 577, out of which 210 patients underwent cesarean sections. The overall cesarean section rate in our study was 36.39%. Previous cesarean section was the leading indication of cesarean section (31.9%) followed by arrest of labor (18.1%), CPD (14.2%), and fetal distress (12.9%). Breech presentation (5.2%), failed induction of labor (4.8%), pregnancy induced hypertension (PIH) (3.8%), oligohydramnios (3.3%), obstructed labor (2.4%), APH (1.4%), multiple pregnancy and BOH accounted for 0.95% of cesarean sections. 9% patients had few complications mainly minor wound infection (2.4%) and postpartum hemorrhage (2%). There was no mortality during this period.Conclusions: Previous cesarean section has been found to be the main indication for cesarean section. So primary cesarean section should be reduced to decrease the overall cesarean rates. A comprehensive, evidence based approach needs to be introduced to monitor indication of all cesarean section.
ABSTRACT
Primary broad ligament pregnancy is a rare form of extrauterine pregnancy with a high maternal and perinatal mortality. Early diagnosis is important to prevent life threatening hemorrhage but can be missed on antenatal ultrasonography. The diagnosis is usually established during laparotomy. We present a case of 22 year old female with ectopic gestation in broad ligament which was missed on ultrasonography and diagnosed during surgery.